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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease li-fraumeni syndrome
Comorbidity C0235974|pancreatic cancer
Sentences 4
PubMedID- 25428385 High expression of rab27a and tp53 in pancreatic cancer predicts poor survival.
PubMedID- 24415872 Methods: human pancreatic cancer cells with wild-type p53 gene (capan-2) and normal pancreatic epithelial cells (h6c7) were cultured in rpmi1640.
PubMedID- 24486587 Patients whose pancreatic cancers had loss of atm but normal tp53 had worse overall survival after pancreatic resection.
PubMedID- 25479140 Background & aims: we investigated the prevalence of germline mutations in apc, atm, brca1, brca2, cdkn2a, mlh1, msh2, msh6, palb2, pms2, prss1, stk11, and tp53 in patients with pancreatic cancer.

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